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BioMed Research International
Volume 2016, Article ID 1736024, 9 pages
http://dx.doi.org/10.1155/2016/1736024
Research Article

Protective Effects of Emodin-Induced Neutrophil Apoptosis via the Ca2+-Caspase 12 Pathway against SIRS in Rats with Severe Acute Pancreatitis

1Pancreaticobiliary Centre, Department of General Surgery, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116044, China
2College of Integrative Medicine, Dalian Medical University, Dalian, Liaoning 116044, China
3Clinical Laboratory of Integrative Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116044, China

Received 1 September 2016; Accepted 26 October 2016

Academic Editor: Kok Tat Tan

Copyright © 2016 Gui-Jun Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [5 citations]

The following is the list of published articles that have cited the current article.

  • Jian-Wen Ning, Yan Zhang, Mo-Sang Yu, Meng-Li Gu, Jia Xu, Ali Usman, and Feng Ji, “Emodin alleviates intestinal mucosal injury in rats with severe acute pancreatitis via the caspase-1 inhibition,” Hepatobiliary & Pancreatic Diseases International, vol. 16, no. 4, pp. 431–436, 2017. View at Publisher · View at Google Scholar
  • Jiming Wu, Le Gao, Lei Shang, Guihua Wang, Nana Wei, Tiantian Chu, Suping Chen, Yujun Zhang, Jian Huang, Jinhui Wang, and Ruichao Lin, “Ecdysterones from Rhaponticum carthamoides (Willd.) Iljin reduce hippocampal excitotoxic cell loss and upregulate mTOR signaling in rats,” Fitoterapia, 2017. View at Publisher · View at Google Scholar
  • Zhijun Dong, Fan Yang, Weili Dong, Nan Yang, Zhihong Chen, Hongfei Yu, and Tiemin Zhang, “Regulation of sericin on retinal endoplasmic reticulum stress specific caspase-12 dependent pathway and inhibition on apoptosis in diabetic rat,” Zhonghua Shiyan Yanke Zazhi/Chinese Journal of Experimental Ophthalmology, vol. 35, no. 12, pp. 1067–1072, 2017. View at Publisher · View at Google Scholar
  • Weipeng Liu, Qingxia Yuan, Shutong Guo, and Zhaoying Fu, “Emodin in Severe Acute Pancreatitis Treatment,” Chinese Medicine, vol. 08, no. 04, pp. 101–112, 2017. View at Publisher · View at Google Scholar
  • Chunsheng Cheng, and Weiguo Dong, “Aloe-emodin induces endoplasmic reticulum stress-dependent apoptosis in colorectal cancer cells,” Medical Science Monitor, vol. 24, pp. 6331–6339, 2018. View at Publisher · View at Google Scholar