BioMed Research International / 2016 / Article / Tab 3

Research Article

Nicotinamide Mononucleotide Adenylyl Transferase 2: A Promising Diagnostic and Therapeutic Target for Colorectal Cancer

Table 3

Comparison of positive expression of NMNAT2 and p53 between different clinical pathological characteristic groups of colorectal cancer.

ParametersPatients () NMNAT2p53
NegativePositive valueNegativePositive value

Gender
 Male509 (18.0%)41 (82.0%)18 (36.0%)32 (64.0%)
 Female458 (17.8%)37 (82.2%)17 (37.8%)28 (62.2%)
Age
 ≥65516 (11.8%)45 (88.2%)18 (35.3%)33 (64.7%)
 <654411 (25.0%)33 (75.0%)17 (38.6%)27 (61.4%)
Morphology
 Ulcerative type6512 (18.5%)53 (81.5%)26 (40.0%)39 (60.0%)
 Polypoid type305 (16.7%)25 (83.3%)9 (30.0%)21 (70.0%)
Histological type
 Adenocarcinoma7713 (16.9%)64 (83.1%)29 (37.7%)48 (62.3%)
 Mucous carcinoma184 (22.2%)14 (77.8%)6 (33.3%)12 (66.7%)
Differentiation
 Well213 (14.3%)18 (85.7%)10 (47.6%)11 (52.4%)
 Middle and poor7414 (18.9%)60 (81.1%)25 (33.8%)49 (66.2%)
Average diameter
 ≥3528 (15.4%)44 (84.6%)17 (32.7%)35 (67.3%)
 <3439 (20.9%)34 (79.1%)18 (41.9%)25 (58.1%)
Depth of invasion
 T1 + T24413 (29.5%)31 (70.5%)25 (56.8%)19 (43.2%)
 T3 + T4514 (7.8%)47 (92.2%)10 (19.6%)41 (80.4%)
Lymph metastasis
 N06014 (23.3%)46 (76.7%)28 (46.7%)32 (53.3%)
 N1 + N2353 (8.6%)32 (91.4%)7 (20.0%)28 (80.0%)
TNM stage
 I + II5614 (25.0%)42 (75.0%)26 (46.4%)30 (53.6%)
 III + IV393 (7.7%)36 (92.3%)9 (23.1%)30 (76.9%)