BioMed Research International / 2016 / Article / Tab 4

Research Article

Nicotinamide Mononucleotide Adenylyl Transferase 2: A Promising Diagnostic and Therapeutic Target for Colorectal Cancer

Table 4

Univariate and multivariate Cox regression analyses of prognostic factors for 5-year survival.

Parameters UnivariateHR (95% CI)Multivariate

Gender
 Male
 Female
Age
 ≥65
 <65
Morphology
 Ulcerative type 3.105 (1.165–8.273)
 Polypoid type
Histological type
 Adenocarcinoma
 Mucous carcinoma
Differentiation
 Well
 Middle and poor
Average diameter
 ≥3 2.993 (1.480–6.054)
 <3
Depth of invasion
 T1 + T2
 T3 + T4
Lymph metastasis
 N0
 N1 + N2
TNM stage
 I + II 4.508 (2.303–8.822)
 III + IV
NMNAT2 expression
 Negative
 Positive
p53 expression
 Negative
 Positive