BioMed Research International / 2016 / Article / Tab 3

Research Article

Evaluation of Bone Metabolism in Critically Ill Patients Using CTx and PINP

Table 3

Demographics, admission diagnosis, and characteristics of the patients according to survival status (n = 28).

VariableSurvivors (n = 18)Nonsurvivors (n = 10)p

Age, (range) yrs65.0 ± 2.571.6 ± 3.20.88
Males, n, %10/18, 55.5%6/10, 60.0%1.0
Admission diagnosis, n
 Pulmonary Infection, RR105
 Pulmonary edema, CHF32
 Complicated surgery22
 SAH/ICH11
 Abdominal sepsis1
 Trauma, head injury1
Type, n
 Medical168
 Surgical22
APACHE II21.9 ± 1.222.7 ± 1.50.58
SAPS II62.9 ± 2.560.1 ± 3.50.83
SOFA9.9 ± 0.910.5 ± 0.90.65
MV duration, days14.3 ± 2.842.8 ± 11.70.039
ICU LOS (median), d18.6 ± 2.9 (13)55.0 ± 12.1 (51.5)0.01
Fever, >38.2°C8/18, 44,4%4/10, 40%1.0
Corrected calcium, mg/dL7.9 ± 0.28.5 ± 0.60.65
Phosphorus, mg/dL3.2 ± 0.33.8 ± 0.30.13
Alkaline phosphatase, mg/dL117.7 ± 19.5124.0 ± 17.10.18
Urea, mg/dL54.5 ± 7.152.8 ± 8.30.96
AST (SGOT), IU/dL51.4 ± 14.931.8 ± 4.61.0
ALT (SGPT), IU/dL90.1 ± 44.431.1 ± 5.90.98
WBC, /mm310,964 ± 1,99711,309 ± 1,8040.79
Creatinine, mg/dL1.1 ± 0.81.2 ± 0.20.51
Albumin, g/dL3.0 ± 0.13.3 ± 0.20.38
CRP, mg/dL112.1 ± 24.297.8 ± 38.90.75
i-CTx (ng/mL)0,96 ± 0,191,49 ± 0,320.098
P1NP (ng/mL)15,46 ± 2,4419,85 ± 5,340.773
i-PTH (pg/mL)215,9 ± 39,68159,6 ± 32,680.533
25-OH Vit. D (ng/mL)6,45 ± 1,493,80 ± 0,940.433
Low-dose steroids, n12/184/10
Shock, nor-adrenaline, n17/1810/10
LMWH, n14/185/10
Fondaparinux (Arixtra), n4/185/10
Transfusions, n, (mean)10/188/10
Phenytoin (Epanutin), n2/181/10
Food supplementation, n18/1810/10
 Enteral18/1810/10
 Parenteral1/181/10
 Both1/181/10
 Micronutrients18/1810/10
 Vitamins18/1810/10

RR: respiratory failure, ICH: intracerebral hemorrhage, SAH: subarachnoid hemorrhage, CHF: congestive heart failure, LMWH: low molecular weight heparin, CRP: c-reactive protein, ICU: intensive care medicine, WBC: white blood cell, APACHE II: Acute Physiology And Chronic Health Evaluation, SOFA: Sequential Organ Failure Assessment, AST: Aspartate Aminotransferase, and ALT: Alanine Aminotransferase.

Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.