Research Article

The Association between NOS3 Gene Polymorphisms and Hypoxic-Ischemic Encephalopathy Susceptibility and Symptoms in Chinese Han Population

Table 1

Demographic and clinical characteristics of the participants with their mother.

CharacteristicsPatientsControls

Children
Sample size ()226212
Gender ()
 Male1221190.2040.701
 Female10493
Gestation week (weeks)38.30 ± 0.9638.36 ± 1.190.5580.577
Birth weight ()
 ≤1000 g637.4880.058
 1001~1499 g5140
 1500~2499 g11796
 ≥2500 g5273
Apgar score ()
 ≤5724916.4040.001
 6~76551
 8~94939
 104073
Grade ()
 Slightly101
 Moderately97
 Severely26
Their mother
Sample size (N)208200
Age (years)26.32 ± 2.1926.19 ± 2.05−0.6150.538
Antepartum weight (Kg)57.73 ± 7.2858.41 ± 7.640.9160.360
Complications (%)
 Hypertension6.45.90.0110.916
 Heart disease2.62.00.0770.781
 Diabetes mellitus8.66.90.3860.534
 Anemia9.710.30.0880.766
Factors in parturient
Conception times of parturient (times)1.22 ± 0.101.21 ± 0.09−1.0560.292
Amniotic fluid volume (L)1.02 ± 0.081.03 ± 0.091.1810.238
Amniotic fluid pollution (%)19.413.72.2620.133
Umbilical cord around the neck (%)17.416.90.0070.934
Premature rupture of membranes (%)2.41.80.0770.781