Curcumin Downregulates Phosphate Carrier and Protects against Doxorubicin Induced Cardiomyocyte Apoptosis

Figure 2

The expression of PiC (Slc25a3) gene was significantly increased by doxorubicin, while curcumin decreased PiC expression. In addition, the PiC in groups of Cur 0 was also significantly increased over time following doxorubicin treatment of the cells. ( versus Cur 0, Dox + at each time point) ( versus negative control (Dox 0 h, Cur 0 min)).