Synergistic Cytotoxic Effect of L-Asparaginase Combined with Decitabine as a Demethylating Agent in Pediatric T-ALL, with Specific Epigenetic Signature

<div>Jurkat and CCRF-CEM did not display synergism between Decitabine and L-asparaginase. CI values &lt;1 indicate synergism; CI = 1 indicates additive effect, whereas values &gt; 1 indicate antagonism.</div>

BioMed Research International

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Figure 5

Figure 5: Synergistic Cytotoxic Effect of L-Asparaginase Combined with Decitabine as a Demethylating Agent in Pediatric T-ALL, with Specific Epigenetic Signature 

Figure 5 | Synergistic Cytotoxic Effect of L-Asparaginase Combined with Decitabine as a Demethylating Agent in Pediatric T-ALL, with Specific Epigenetic Signature 