Early Administration of Glutamine Protects Cardiomyocytes from Post-Cardiac Arrest Acidosis

Figure 4

L-glutamine increased the beating function of cardiomyocytes, especially under lower pH conditions. (a) The mean BPM of cardiomyocytes was significantly higher among cells treated with 50 mM L-glutamine in pH 7.3 HBSS buffer than among those that were not treated with L-glutamine. (b) Cardiomyocytes were nearly not beating from the 45th minute after pH 6.5 exposure, but additional exposure to 50 mM L-glutamine could maintain and increase the mean BPM of the cells. One-way ANOVA was used at different time points after treatment with L-glutamine. BPM: beats per minute.

(a)

(b)