Comparison of FDA Approved Kinase Targets to Clinical Trial Ones: Insights from Their System Profiles and Drug-Target Interaction Networks

<div>Distribution of all clinical trial kinase targets (orange) and established kinase targets (red) with respect to (a) the number of human similarity proteins (NS) outside the target family, (b) the number of human pathways (NP) the target is associated with, and (c) the number of human tissues (NT) the target is distributed in.</div>

BioMed Research International

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Figure 4

Figure 4: Comparison of FDA Approved Kinase Targets to Clinical Trial Ones: Insights from Their System Profiles and Drug-Target Interaction Networks 