Effect of Dynamic Interaction between microRNA and Transcription Factor on Gene Expression

Figure 1

The coherent and incoherent feedforward loops. Arrows mean activation, the turned-over T-bars indicate repression. (a) Type 1 coherent FFL, TF activates target gene and represses miRNA synthesis. (b) Type 2 coherent FFL, TF represses target gene and activates miRNA synthesis. (c) Type 1 incoherent FFL, TF activates both target gene and miRNA synthesis. (d) Type 2 incoherent FFL, TF represses both target gene and miRNA synthesis.

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(b)

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