BioMed Research International / 2016 / Article / Fig 3

Research Article

PIPINO: A Software Package to Facilitate the Identification of Protein-Protein Interactions from Affinity Purification Mass Spectrometry Data

Figure 3

Different network layouts in different detail levels. (a) A specialized STAT1-centric network containing experimentally and literature derived PPIs arranged by a force field. (b) The same data depicted with a radial layout. (c) The corresponding truncated network arranged by a force field. (d) A detailed zoom-in of the hierarchical layout. (e) A truncated subnetwork with a scoring threshold of 0.85. Green nodes represent interaction partners not found in the experiment (only listed in database entries), the blue nodes are confirmed interaction partners (found in the databases and the experiment), and the red nodes represent the protein of interest.

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