Recent Advances in Treatments of Primary Focal Segmental Glomerulosclerosis in Children

Table 1

The “Mendoza” protocol for steroid-resistant nephrotic syndrome in children.

Week	Methylprednisolone, 30 mg/kg	Oral prednisone
1-2	Every other day, 6 doses	None
3–10	Every week, 8 doses	2 mg/kg every other day
11–18	Every 2 weeks, 4 doses	With/without taper
19–50	Every 4 weeks, 8 doses	Slow taper
51–82	Every 8 weeks, 4 doses	Slow taper