Phytochemical Screening and Antinociceptive and Antidiarrheal Activities of Hydromethanol and Petroleum Benzene Extract of Microcos paniculata Barks

Table 2

Effect of standard, HMPB, and PBMPB in formalin-induced paw licking test.

Group	Dose	Licking in acute phase (s)	Inhibition (%)	Licking in delayed phase (s)	Inhibition (%)
Control	10 mL/kg	220.40 ± 2.16	0.00 ± 0.00	75.80 ± 1.43	0.00 ± 0.00
DS	100 mg/kg	142.60 ± 3.40	35.31 ± 1.35	7.40 ± 0.51	90.27 ± 0.49
HMPB	200 mg/kg	112.40 ± 2.50	49.02 ± 0.73	62.40 ± 1.03	17.60 ± 1.64
HMPB	400 mg/kg	53.20 ± 2.13	75.87 ± 0.90	45.20 ± 1.16	40.35 ± 1.30
PBMPB	200 mg/kg	58.60 ± 1.50	73.40 ± 0.76	22.80 ± 1.36	70.01 ± 1.22
PBMPB	400 mg/kg	52.40 ± 0.87	76.22 ± 0.39	10.20 ± 0.37	86.56 ± 0.27

Values of the first and second 5 min are presented as mean ± standard error. mice in each group. ⁢, versus control (Dunnett’s -test); , versus DS 100 mg/kg; , versus HMPB 200 mg/kg; , versus HMPB 400 mg/kg; , versus PBMPB 200 mg/kg; , versus PBMPB 400 mg/kg (pairwise comparison by post hoc Tukey’s HSD test).