Research Article
The NLRP3 rs10754558 Polymorphism Is Associated with the Occurrence and Prognosis of Coronary Artery Disease in the Chinese Han Population
Table 3
Baseline characteristics of CAD patients with and without MACE during follow-up.
| ā | Patients without MACE | Patients with MACE | |
| Total, | 358 | 145 | ā | Male, (%) | 240 (67.04%) | 118 (81.38%) | 0.001 | Age, y (mean SD) | 58.52 11.58 | 61.75 11.05 | 0.004 | Hypertension (%) | 188 (52.51%) | 93 (64.14%) | 0.018 | DM (%) | 77 (21.51%) | 52 (35.86%) | 0.001 | Smoking (%) | 159 (44.41%) | 84 (57.93%) | 0.008 | SBp (mmHg) | 125.79 23.71 | 125.34 21.64 | 0.843 | DBp (mmHg) | 78.73 14.16 | 78.39 14.01 | 0.802 | HR (beats/min) | 73.44 16.92 | 71.37 16.79 | 0.212 | BMI (kg/m2) | 24.63 2.71 | 25.20 3.22 | 0.045 | LVEF (%) | 57.58 12.03 | 55.54 11.79 | 0.085 | Hs-CRP (mg/L) | 5.76 2.24 | 6.34 3.64 | 0.029 | TC (mmol/L) | 3.91 0.95 | 4.09 0.99 | 0.060 | TG (mmol/L) | 1.69 0.72 | 1.73 0.82 | 0.590 | HDL-C (mmol/L) | 0.99 0.25 | 0.88 0.22 | 0.001 | LDL-C (mmol/L) | 2.26 0.74 | 2.51 0.87 | 0.001 | ACE-I/ARB, (%) | 247 (68.99%) | 96 (66.21%) | 0.527 | Statins, (%) | 343 (95.81%) | 134 (92.41%) | 0.124 | -blocker, (%) | 246 (68.72%) | 105 (72.41%) | 0.454 | Aspirin, (%) | 344 (96.09%) | 137 (94.48%) | 0.471 |
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CAD: coronary artery disease; MACE: major adverse cardiacevent; SBp: systolic blood pressure; DBp: diastolic blood pressure; HR: heart rate; BMI: body mass index; LVEF: left ventricular ejection fraction; Hs-CRP: high-sensitivity C-reactive protein; TC: total cholesterol; TG: triglyceride; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; DM: diabetes mellitus; ACEI: angiotensin converting enzyme inhibitor; ARB: angiotensin receptor antagonist.
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