Research Article

The NLRP3 rs10754558 Polymorphism Is Associated with the Occurrence and Prognosis of Coronary Artery Disease in the Chinese Han Population

Table 3

Baseline characteristics of CAD patients with and without MACE during follow-up.

ā€‰Patients without MACEPatients with MACE

Total, 358145ā€‰
Male, (%)240 (67.04%)118 (81.38%)0.001
Age, y (mean SD)58.52 11.5861.75 11.050.004
Hypertension (%)188 (52.51%)93 (64.14%)0.018
DM (%)77 (21.51%)52 (35.86%)0.001
Smoking (%)159 (44.41%)84 (57.93%)0.008
SBp (mmHg)125.79 23.71125.34 21.640.843
DBp (mmHg)78.73 14.1678.39 14.010.802
HR (beats/min) 73.44 16.9271.37 16.790.212
BMI (kg/m2)24.63 2.7125.20 3.220.045
LVEF (%)57.58 12.0355.54 11.790.085
Hs-CRP (mg/L)5.76 2.246.34 3.640.029
TC (mmol/L)3.91 0.954.09 0.990.060
TG (mmol/L)1.69 0.721.73 0.820.590
HDL-C (mmol/L)0.99 0.250.88 0.220.001
LDL-C (mmol/L)2.26 0.742.51 0.870.001
ACE-I/ARB, (%)247 (68.99%)96 (66.21%)0.527
Statins, (%)343 (95.81%)134 (92.41%)0.124
-blocker, (%)246 (68.72%)105 (72.41%)0.454
Aspirin, (%)344 (96.09%)137 (94.48%)0.471

CAD: coronary artery disease; MACE: major adverse cardiacevent; SBp: systolic blood pressure; DBp: diastolic blood pressure; HR: heart rate; BMI: body mass index; LVEF: left ventricular ejection fraction; Hs-CRP: high-sensitivity C-reactive protein; TC: total cholesterol; TG: triglyceride; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; DM: diabetes mellitus; ACEI: angiotensin converting enzyme inhibitor; ARB: angiotensin receptor antagonist.