Antidermatophytic Activity of Ethanolic Extract from Croton tiglium

Table 1

Antifungal activity of Croton tiglium ethanolic extracts against Trichophyton mentagrophytes by the disc diffusion method.

Specimen		Stem		Leave		Seed
		Heat reflux	Cold soak	Heat reflux	Cold soak	Heat reflux	Cold soak
Extract	10 g	11.1 ± 0.4	8.7 ± 0.3	8.0 ± 0.0	8.0 ± 0.0	9.5 ± 0.4	9.1 ± 0.3
	50 g	14.0 ± 0.4	11.7 ± 0.2	9.6 ± 0.3	8.7 ± 0.5	13.0 ± 0.6	11.7 ± 0.6
	250 g	17.0 ± 0.2	14.2 ± 0.6	12.5 ± 0.2	11.1 ± 0.2	16.1 ± 0.8	14.4 ± 0.7
	500 g	18.1 ± 0.4	15.2 ± 0.4	13.4 ± 0.1	12.4 ± 0.8	17.3 ± 0.7	15.4 ± 0.8
AMB (10 g)		21.3 ± 0.2

The fungal spores were plated on SDA plates with the extracts or amphotericin B (AMB) absorbed on 8 mm filter paper discs. Duncan’s multiple range test () was used to statistically evaluate the difference in the diameters (mm) of inhibition zones. The letters “a, b, c, d, and e” indicated significant differences between groups treated with different amounts of the extracts. The letters “w, x, y, and z” indicate statistical differences among the extraction groups.