Complement Factor 3 Could Be an Independent Risk Factor for Mortality in Patients with HBV Related Acute-on-Chronic Liver Failure

Figure 5

Survival rate varied depending on C3 levels. Pooled data indicated the levels of C3, C4, and CH50 in patients who died () and those who survived (), where the lines indicated the median. Serum C3 levels were significantly lower in HBV-ACLF patients who died compared to patients who survived (a). However, no significant differences in serum C4 or CH50 levels were found between them (b and c). (d) Using the Kaplan-Meier analysis, the log-rank test revealed that a significant difference existed among three groups according to C3 levels, and patients with a high grade of C3 had a significantly higher survival rate compared to those with moderate grade or low grade (log-rank 15.443, ). ; ns, not significant.

(a)

(b)

(c)

(d)