Histopathological Evaluation of Contrast-Induced Acute Kidney Injury Rodent Models

Figure 1

Use of contrast materials in the USA. The most common cause of intravenous iodinated contrast media [27] is X-ray (75 million/year) while about 50% of the CT and MRI studies are also contrast enhanced accounting for another 38 million patients/year. The degree of contrast utilization is expected to increase in the future [28]. The global market for radiopharmaceuticals is $4.5 billion in 2015 and is projected to reach US$ 6.63 billion by 2017 [29]. The iodinated, injectable contrast agents segment is expected to account for the largest share of the contrast agents market [30].