BioMed Research International / 2016 / Article / Tab 4 / Research Article
A Novel Peptide Binding Prediction Approach for HLA-DR Molecule Based on Sequence and Structural Information Table 4 Comparison of our binding prediction with other approaches. The 5th column is the result of our method, and 6th to 8th columns are results of TEPITOPE, MultiRTA, and NetMHCIIpan. The bold cell means one error.
PDB ID Allele Peptide Core Ours TEPITOPE MultiRTA NetMHCIIpan-2.0 1AQD DRB1 VGSDWRFLRGYHQYA WRFLRGYHQ WRFLRGYHQ WRFLRGYHQ WRFLRGYHQ WRFLRGYHQ 1PYW DRB1 XFVKQNAAALX FVKQNAAAL FVKQNAAAL FVKQNAAAL FVKQNAAAL FVKQNAAAL 1KLG DRB1 GELIGILNAAKVPAD IGILNAAKV IGILNAAKV IGILNAAKV IGILNAAKV LIGILNAAK 2FSE DRB1 GELIGTLNAAKVPAD IGTLNAAKV IGTLNAAKV IGTLNAAKV IGTLNAAKV IGTLNAAKV 1KLU DRB1 AGFKGEQGPKGEPG FKGEQGPKG FKGEQGPKG FKGEQGPKG FKGEQGPKG FKGEQGPKG 1SJH DRB1 PEVIPMFSALSEG VIPMFSALS VIPMFSALS VIPMFSALS VIPMFSALS VIPMFSALS 1SJE DRB1 PEVIPMFSALSEGATP VIPMFSALS VIPMFSALS VIPMFSALS VIPMFSALS VIPMFSALS 1T5W DRB1 AAYSDQATPLLLSPR YSDQATPLL SDQATPLLL YSDQATPLL SDQATPLLL YSDQATPLL 1T5X DRB1 AAYSDQATPLLLSPR YSDQATPLL SDQATPLLL YSDQATPLL SDQATPLLL YSDQATPLL 2IAN DRB1 GELIGTLNAAKVPAD IGTLNAAKV IGTLNAAKV IGTLNAAKV IGTLNAAKV IGTLNAAKV 2IPK DRB1 GELIGILNAAKVPAD IGILNAAKV IGILNAAKV IGILNAAKV IGILNAAKV LIGILNAAK 1FYT DRB1 XPKWVKQNTLKLAT WVKQNTLKL WVKQNTLKL WVKQNTLKL WVKQNTLKL WVKQNTLKL 1R5I DRB1 PKYVKQNTLKLAT YVKQNTLKL YVKQNTLKL YVKQNTLKL YVKQNTLKL YVKQNTLKL 1HXY DRB1 PKYVKQNTLKLAT YVKQNTLKL YVKQNTLKL YVKQNTLKL YVKQNTLKL YVKQNTLKL 1JWM DRB1 PKYVKQNTLKLAT YVKQNTLKL YVKQNTLKL YVKQNTLKL YVKQNTLKL YVKQNTLKL 1JWS DRB1 PKYVKQNTLKLAT YVKQNTLKL YVKQNTLKL YVKQNTLKL YVKQNTLKL YVKQNTLKL 1JWU DRB1 PKYVKQNTLKLAT YVKQNTLKL YVKQNTLKL YVKQNTLKL YVKQNTLKL YVKQNTLKL 1LO5 DRB1 PKYVKQNTLKLAT YVKQNTLKL YVKQNTLKL YVKQNTLKL YVKQNTLKL YVKQNTLKL 2ICW DRB1 PKYVKQNTLKLAT YVKQNTLKL YVKQNTLKL YVKQNTLKL YVKQNTLKL YVKQNTLKL 2OJE DRB1 PKYVKQNTLKLAT YVKQNTLKL YVKQNTLKL YVKQNTLKL YVKQNTLKL YVKQNTLKL 2G9H DRB1 PKYVKQNTLKLAT YVKQNTLKL YVKQNTLKL YVKQNTLKL YVKQNTLKL YVKQNTLKL 2IAM DRB1 PKYVKQNTLKLAT YVKQNTLKL YVKQNTLKL YVKQNTLKL YVKQNTLKL YVKQNTLKL 1A6A DRB1 PVSKMRMATPLLMQA MRMATPLLM MRMATPLLM MRMATPLLM MRMATPLLM MRMATPLLM 1J8H DRB1 PKYVKQNTLKLAT YVKQNTLKL YVKQNTLKL YVKQNTLKL YVKQNTLKL YVKQNTLKL 2SEB DRB1 AYMRADAAAGGA MRADAAAGG MRADAAAGG MRADAAAGG MRADAAAGG YMRADAAAG 1BX2 DRB1 ENPVVHFFKNIVTPR VHFFKNIVT VHFFKNIVT VHFFKNIVT VHFFKNIVT VVHFFKNIV 1YMM DRB1 ENPVVHFFKNIVTPRGGSGGGGG VHFFKNIVT VHFFKNIVT VHFFKNIVT VHFFKNIVT VHFFKNIVT 1FV1 DRB5 NPVVHFFKNIVTPRTPPPSQ FKNIVTPRT KNIVTPRTP FKNIVTPRT VHFFKNIVT FFKNIVTPR 1H15 DRB5 GGVYHFVKKHVHES YHFVKKHVH YHFVKKHVH YHFVKKHVH YHFVKKHVH YHFVKKHVH 1ZGL DRB5 VHFFKNIVTPRTPGG FKNIVTPRT KNIVTPRTP FKNIVTPRT VHFFKNIVT FFKNIVTPR Results 4 errors 0 errors 4 errors 6 errors
