Approaches to Peripheral Nerve Repair: Generations of Biomaterial Conduits Yielding to Replacing Autologous Nerve Grafts in Craniomaxillofacial Surgery

Table 3

FDA approved nerve guidance conduits.

Product	Material	Structure	Degradation time	Company	FDA-approval
NeuroTube	Polyglycolic acid	Absorbable woven mesh tube	3 mo	Synovis Micro Companies	1999
NeuraGen	Type I collagen	Semipermeable, fibrillar	3-4 yrs	Integra LifeSciences Co., Plainsboro, NJ, USA	2001
NeuroFlex	Type I collagen	Semipermeable, flexible, tubular	4–8 mo	Collagen Matrix, Inc., Franklin	2001
NeuroMatrix	Type I collagen	Semipermeable, flexible, tubular	4–8 mo	Collagen Matrix, Inc.	2001
NeuraWrap	Type I collagen	Semipermeable, longitudinal slit in wall	36–48 mo	Integra LifeSciences Co.	2004
NeuroMend	Type I collagen	Semipermeable wrap, unrolls and self-curls	4–8 mo	Collagen Matrix, Inc.	2006
Neurolac	Poly-DL-lactide-caprolactone	Synthetic and transparent, tubular	16 mo	Polyganics BV, Groningen, Netherlands	2003
SaluTunnel	Polyvinyl alcohol	Nonbiodegradable	No degradation	Salumedica LLC, Atlanta, GA, USA	2010
Avance	⁢Processed human nerve allograft			AxoGen, Inc., Alachua, FL	2010
AxoGuard	Extracellular matrix derived from porcine small intestine submucosa	Absorbable semipermeable	No data	AxoGen, Inc., Alachua, FL	2013