Approaches to Peripheral Nerve Repair: Generations of Biomaterial Conduits Yielding to Replacing Autologous Nerve Grafts in Craniomaxillofacial Surgery

Table 5

Clinical studies on facial nerve reconstruction with FDA approved nerve guidance conduits.

Study	Year	Product	Type of research	Species	Defect/pathology	Case count	Functional recovery attained
Navissano et al. [39]	2005	NeuroTube	Case report	Human	1–3 cm	7	Yes (71% of the cases)
Dwivedi et al. [40]	2006	NeuraGen	Case report	Human	Hypoglossal-facial anastomosis	1	Yes
Gunn et al. [41]	2010	Avance	Case report	Human	Paraganglioma	1	Yes
Brant et al. [42]	2016	Avance/AxoGuard	Technical report	Human	Facial nerve schwannoma	1	n/a