Table of Contents Author Guidelines Submit a Manuscript
Table of Contents Alerts

To receive news and publication updates for BioMed Research International, enter your email address in the box below.

BioMed Research International
Volume 2016, Article ID 3968206, 5 pages
http://dx.doi.org/10.1155/2016/3968206
Research Article

Modulation of Circulating MicroRNAs Levels during the Switch from Clopidogrel to Ticagrelor

Annarita Carino,1 Salvatore De Rosa,1 Sabato Sorrentino,1 Alberto Polimeni,1 Jolanda Sabatino,1 Gianluca Caiazzo,1 Daniele Torella,1 Carmen Spaccarotella,1 Annalisa Mongiardo,1 Antonio Strangio,1 Carol Filippis,1 and Ciro Indolfi1,2

1Division of Cardiology, Department of Medical and Surgical Sciences, Magna Græcia University, 88100 Catanzaro, Italy
2URT-CNR, Department of Medicine, Consiglio Nazionale delle Ricerche, 88100 Catanzaro, Italy

Received 30 January 2016; Revised 20 April 2016; Accepted 15 May 2016

Academic Editor: Laurent Metzinger

Copyright © 2016 Annarita Carino et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. M. J. Davies and A. Thomas, “Thrombosis and acute coronary-artery lesions in sudden cardiac ischemic death,” The New England Journal of Medicine, vol. 310, no. 18, pp. 1137–1140, 1984. View at Publisher · View at Google Scholar · View at Scopus
  2. S. De Rosa, A. Curcio, and C. Indolfi, “Emerging role of micrornas in cardiovascular diseases,” Circulation Journal, vol. 78, no. 3, pp. 567–575, 2014. View at Publisher · View at Google Scholar · View at Scopus
  3. P. S. Mitchell, R. K. Parkin, E. M. Kroh et al., “Circulating microRNAs as stable blood-based markers for cancer detection,” Proceedings of the National Academy of Sciences of the United States of America, vol. 105, no. 30, pp. 10513–10518, 2008. View at Publisher · View at Google Scholar · View at Scopus
  4. S. De Rosa and C. Indolfi, “Circulating microRNAs as biomarkers in cardiovascular diseases,” in Circulating microRNAs in Disease Diagnostics and their Potential Biological Relevance, vol. 106 of Experientia Supplementum, pp. 139–149, Springer, 2015. View at Publisher · View at Google Scholar
  5. P. Diehl, A. Fricke, L. Sander et al., “Microparticles: major transport vehicles for distinct microRNAs in circulation,” Cardiovascular Research, vol. 93, no. 4, pp. 633–644, 2012. View at Publisher · View at Google Scholar · View at Scopus
  6. S. De Rosa, S. Fichtlscherer, R. Lehmann, B. Assmus, S. Dimmeler, and A. M. Zeiher, “Transcoronary concentration gradients of circulating microRNAs,” Circulation, vol. 124, no. 18, pp. 1936–1944, 2011. View at Publisher · View at Google Scholar · View at Scopus
  7. P. Willeit, A. Zampetaki, K. Dudek et al., “Circulating microRNAs as novel biomarkers for platelet activation,” Circulation Research, vol. 112, no. 4, pp. 595–600, 2013. View at Publisher · View at Google Scholar · View at Scopus
  8. G. Caiazzo, S. De Rosa, D. Torella et al., “Administration of a loading dose has no additive effect on platelet aggregation during the switch from ongoing clopidogrel treatment to ticagrelor in patients with acute coronary syndrome,” Circulation: Cardiovascular Interventions, vol. 7, no. 1, pp. 104–112, 2014. View at Publisher · View at Google Scholar · View at Scopus
  9. S. Fichtlscherer, S. De Rosa, H. Fox et al., “Circulating microRNAs in patients with coronary artery disease,” Circulation Research, vol. 107, no. 5, pp. 677–684, 2010. View at Publisher · View at Google Scholar · View at Scopus
  10. B. Chyrchel, J. Totoń-Żurańska, O. Kruszelnicka et al., “Association of plasma MIR-223 and platelet reactivity in patients with coronary artery disease on dual antiplatelet therapy: a preliminary report,” Platelets, vol. 26, no. 6, pp. 593–597, 2015. View at Publisher · View at Google Scholar · View at Scopus
  11. L. C. Edelstein and P. F. Bray, “MicroRNAs in platelet production and activation,” Blood, vol. 117, no. 20, pp. 5289–5296, 2011. View at Publisher · View at Google Scholar · View at Scopus
  12. J. B. Opalinska, A. Bersenev, Z. Zhang et al., “MicroRNA expression in maturing murine megakaryocytes,” Blood, vol. 116, no. 23, pp. e128–e138, 2010. View at Publisher · View at Google Scholar · View at Scopus
  13. A. A. Kondkar, M. S. Bray, S. M. Leal et al., “VAMP8/endobrevin is overexpressed in hyperreactive human platelets: suggested role for platelet microRNA,” Journal of Thrombosis and Haemostasis, vol. 8, no. 2, pp. 369–378, 2010. View at Publisher · View at Google Scholar · View at Scopus
  14. H. Bruchova, M. Merkerova, and J. T. Prchal, “Aberrant expression of microRNA in polycythemia vera,” Haematologica, vol. 93, no. 7, pp. 1009–1016, 2008. View at Publisher · View at Google Scholar · View at Scopus
  15. A. Zampetaki, P. Willeit, L. Tilling et al., “Prospective study on circulating microRNAs and risk of myocardial infarction,” Journal of the American College of Cardiology, vol. 60, no. 4, pp. 290–299, 2012. View at Publisher · View at Google Scholar · View at Scopus
  16. B. Laffont, A. Corduan, M. Rousseau et al., “Platelet microparticles reprogram macrophage gene expression and function,” Thrombosis and Haemostasis, vol. 115, no. 2, pp. 311–323, 2016. View at Publisher · View at Google Scholar
  17. R. Shi, X. Zhou, W. J. Ji et al., “The emerging role of miR-223 in platelet reactivity: implications in antiplatelet therapy,” BioMed Research International, vol. 2015, Article ID 981841, 8 pages, 2015. View at Publisher · View at Google Scholar
  18. M. L. Coluccio, F. Gentile, G. Das et al., “Detection of single amino acid mutation in human breast cancer by disordered plasmonic self-similar chain,” Science Advances, vol. 1, no. 8, Article ID e1500487, 2015. View at Publisher · View at Google Scholar
  19. C. Gareri, S. De Rosa, and C. Indolfi, “MicroRNAs for restenosis and thrombosis after vascular injury,” Circulation Research, vol. 118, no. 7, pp. 1170–1184, 2016. View at Publisher · View at Google Scholar
  20. D. D. McManus and J. E. Freedman, “MicroRNAs in platelet function and cardiovascular disease,” Nature Reviews Cardiology, vol. 12, pp. 711–717, 2015. View at Publisher · View at Google Scholar · View at Scopus