Clinical Study

Demineralized Bone Matrix Add-On for Acceleration of Bone Healing in Atypical Subtrochanteric Femoral Fracture: A Consecutive Case-Control Study

Table 1

Preoperative patients’ characteristics.

NDBM group ()DBM group () value

Age, year70 763 80.08
Female gender9 (100)8 (89)1.00
Fracture on right side4 (44)6 (67)0.64
BMI, 22.4 2.424.1 3.20.22
Comorbid diseases
 Rheumatoid arthritis0 (0)2 (22)0.47
 Diabetes2 (22)1 (11)1.00
 Renal disease1 (11)2 (22)1.00
Medications used
 BPs8 (89)9 (100)1.00
 Statin4 (44)4 (44)1.00
 Steroids1 (11)3 (33)0.58
 PPIs4 (44)3 (33)0.62
Duration of BPs before fracture, year8.9 2.97.6 3.90.41
Preoperative laboratory values
 Hb, g/dL11.7 1.412.0 1.80.72
 Albumin, g/L37.5 2.633.1 7.40.14
 CrCl, mL/minute/1.73 m368.4 26.876.0 31.80.59
 Calcium, mg/dL9.2 0.78.6 0.60.07
 Inorganic phosphate, mg/dL3.4 0.33.3 0.70.73
 25-OH vitamin D, ng/mL28.8 9.327.8 11.60.88
 Total P1NP, ng/mL46.4 60.855.0 64.80.8
-cross laps, ng/mL0.24 0.210.23 0.190.99
 PTH, pg/mL50.5 47.951.2 22.80.97
Follow-up time, week125 6072 40

Value presented as mean standard deviation. Value presented as number of patients (percentage).
BMI: body mass index; BPs: bisphosphonates; PPIs: proton pump inhibitors; Hb: hemoglobin.
CrCl: creatinine clearance; P1NP: procollagen type 1 N-terminal propeptide.
CTX: collagen type 1 C-telopeptide; PTH: parathyroid hormone.
Calculated only from the patients receiving BPs. Significant value as .