High Glucose-Induced PC12 Cell Death by Increasing Glutamate Production and Decreasing Methyl Group Metabolism

Figure 4

PLS-DA results obtained from NMR-based intracellular metabolome in the control () and HG () groups: (a) score plot; (b) validation plot by permutation tests (200 cycles); (c) loading plot colored according to the absolute value of the correlation coefficient.

(a)

(b)

(c)