Clinical Study
The -174G/C Interleukin-6 Gene Promoter Polymorphism as a Genetic Marker of Differences in Therapeutic Response to Methotrexate and Leflunomide in Rheumatoid Arthritis
Table 2
Comparison of clinical and laboratory characteristics at the baseline between GG genotype carriers and GC or CC genotype carriers.
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GG: excisable homozygote genotype; GC: heterozygote genotype; CC: homozygote genotype; RA: rheumatoid arthritis; HAQ-Di: Health Assessment Questionnaire-Disability index; DAS-28: modified Disease Activity Score (28 joints); IL-6: interleukin-6 serum levels. Qualitative variables were expressed in frequencies (%); quantitative variables were expressed in means ± standard deviations (SD). Comparisons between differences in proportions were performed with chi-square test (or Fisher exact test if applicable). Comparisons between differences in means were performed using independent samples Student’s -tests. |