Integrated Analysis of DNA Methylation and mRNA Expression Profiles Data to Identify Key Genes in Lung Adenocarcinoma
Table 2
The 29 lung adenocarcinoma-associated methylation sites located in 27 DEGs.
IllumID
Chromosome
Meth.pos (Genome Build 36)
DEG
Distance_to_TSS
cg17398595
chr9
17568725
SH3GL2
469
cg01817029
chr12
70951777
TRHDE
953
cg18182399
chr2
219991419
DES
76
cg01532771
chr19
7733560
CLEC4M
521
cg17407908
chr6
32261093
AGER
1092
cg21057494
chr3
45041975
CLEC3B
799
cg08555612
chr3
71917330
PROK2
428
cg04884908
chr2
72228348
CYP26B1
123
cg06615154
chr1
151789177
S100A3
819
cg10244047
chr6
69402835
BAI3
1323
cg18343862
chr11
10546579
XLKD1
276
cg01880569
chr16
81217829
CDH13
250
cg08977371
chr16
81217991
CDH13
88
cg24829483
chr4
14950739
C1QTNF7
29
cg08448751
chr3
52454641
SEMA3G
558
cg03382304
chr21
25934047
JAM2
587
cg02992632
chr3
193928074
FGF12
8
cg09137696
chr16
55229916
MT1A
163
cg03192737
chr3
192413893
OSTN
877
cg10031651
chr3
46596690
LRRC2
114
cg05564657
chr3
153014065
AADAC
486
cg06866657
chr9
124030575
LHX6
230
cg08831744
chr7
45927871
IGFBP3
475
1.023873571
cg03462055
chr6
3172555
TUBB2B
315
1.175827143
cg00910067
chr19
38409385
SLC7A10
837
1.289525714
cg05976074
chr19
38408113
SLC7A10
435
1.289525714
cg14546153
chr20
56523721
FLJ90166
366
1.331159286
cg00616129
chr12
10718281
STYK1
375
1.541281786
cg23582408
chr20
61600555
EEF1A2
394
2.431418571
Note: IllumID represents probe name. Meth.pos stands for the position of methylation site in genome. Distance_to_TSS indicates the distance of methylation site from transcriptional start site of downstream gene. β in represents methylation index of methylation probe.