Corneal Dendritic Cell Density Is Associated with Subbasal Nerve Plexus Features, Ocular Surface Disease Index, and Serum Vitamin D in Evaporative Dry Eye Disease

Table 2

Correlation of OSDI scores with corneal dendritic cell density and corneal subbasal nerve plexus features in EDE patients.

	OSDI—discomfort		OSDI—vision		OSDI—total
		value		value		value
Dendritic cells
Total cells (cells/mm^2)	0.348	0.0003	−0.104	0.2925	0.161	0.1028
DCs with dendrites (cells/mm^2)	0.274	0.0048	−0.039	0.6937	0.126	0.2016
DCs without dendrites (cells/mm^2)	0.347	0.0003	−0.118	0.2335	0.162	0.0999
Subbasal nerve plexus
CNFL (length in mm/mm^2)	0.148	0.1342	0.079	0.427	0.157	0.112
CNFD (major nerves/mm^2)	0.097	0.3292	0.167	0.0897	0.153	0.1215
CNFW (average nerve fiber width/mm^2)	0.009	0.9247	0.009	0.9259	0.027	0.7824
CTBD (branch points/mm^2)	0.124	0.2101	0.009	0.9249	0.102	0.3027
CNBD (number of branches/mm^2)	0.094	0.3411	0.073	0.459	0.117	0.2352
CNFA (total nerve fiber area/mm^2)	0.18	0.067	−0.103	0.2991	0.07	0.4787

OSDI: ocular surface disease index; DCs: dendritic cells; CNFL: corneal nerve fiber length; CNFD: corneal nerve fiber density; CNFW: corneal nerve fiber width; CTBD: corneal total branch density; CNBD: corneal nerve branch density; CNFA: corneal nerve fiber area; : Spearman correlation coefficient.