Table of Contents Author Guidelines Submit a Manuscript
BioMed Research International
Volume 2016, Article ID 4874195, 6 pages
http://dx.doi.org/10.1155/2016/4874195
Research Article

RANK Expression and Osteoclastogenesis in Human Monocytes in Peripheral Blood from Rheumatoid Arthritis Patients

Institute of Rheumatology, Tokyo Women’s Medical University, 10-22 Kawada-cho, Shinjuku-ku, Tokyo 162-0054, Japan

Received 16 May 2016; Revised 1 August 2016; Accepted 7 August 2016

Academic Editor: Samuel Huber

Copyright © 2016 Yuki Nanke et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. S. Kotake, Y. Nanke, M. Mogi et al., “IFN-γ-producing human T cells directly induce osteoclastogenesis from human monocytes via the expression of RANKL,” European Journal of Immunology, vol. 35, no. 11, pp. 3353–3363, 2005. View at Publisher · View at Google Scholar · View at Scopus
  2. G. J. Atkins, P. Kostakis, C. Vincent et al., “RANK expression as a cell surface marker of human osteoclast precursors in peripheral blood, bone marrow, and giant cell tumors of bone,” Journal of Bone and Mineral Research, vol. 21, no. 9, pp. 1339–1349, 2006. View at Publisher · View at Google Scholar · View at Scopus
  3. Y. Kochi, Y. Okada, A. Suzuki et al., “A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility,” Nature Genetics, vol. 42, no. 6, pp. 515–519, 2010. View at Publisher · View at Google Scholar · View at Scopus
  4. K. Hirota, H. Yoshitomi, M. Hashimoto et al., “Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model,” Journal of Experimental Medicine, vol. 204, no. 12, pp. 2803–2812, 2007. View at Publisher · View at Google Scholar · View at Scopus
  5. F. C. Arnett, S. M. Edworthy, D. A. Bloch et al., “The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis,” Arthritis and Rheumatism, vol. 31, no. 3, pp. 315–324, 1988. View at Publisher · View at Google Scholar · View at Scopus
  6. S. Kotake, Y. Nanke, T. Yago, M. Kawamoto, and H. Yamanaka, “Human osteoclastogenic T cells and human osteoclastology,” Arthritis and Rheumatism, vol. 60, no. 11, pp. 3158–3163, 2009. View at Publisher · View at Google Scholar · View at Scopus
  7. S. Kotake, N. Udagawa, N. Takahashi et al., “IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis,” The Journal of Clinical Investigation, vol. 103, no. 9, pp. 1345–1352, 1999. View at Publisher · View at Google Scholar · View at Scopus
  8. M. M. Zaiss, R. Axmann, J. Zwerina et al., “Treg cells suppress osteoclast formation: a new link between the immune system and bone,” Arthritis and Rheumatism, vol. 56, no. 12, pp. 4104–4112, 2007. View at Publisher · View at Google Scholar · View at Scopus
  9. S. Tanaka, “Regulation of bone destruction in rheumatoid arthritis through RANKL-RANK pathways,” World Journal of Orthopaedics, vol. 4, no. 1, pp. 1–6, 2013. View at Publisher · View at Google Scholar · View at Scopus
  10. H. Takayanagi, “SnapShot: osteoimmunology,” Cell Metabolism, vol. 21, article 502, 2015. View at Publisher · View at Google Scholar · View at Scopus
  11. S. Tanida, H. Yoshitomi, K. Nishitani et al., “CCL20 produced in the cytokine network of rheumatoid arthritis recruits CCR6+ mononuclear cells and enhances the production of IL-6,” Cytokine, vol. 47, no. 2, pp. 112–118, 2009. View at Publisher · View at Google Scholar · View at Scopus
  12. G. Lisignoli, A. Piacentini, S. Cristino et al., “CCL20 chemokine induces both osteoblast proliferation and osteoclast differentiation: increased levels of CCL20 are expressed in subchondral bone tissue of rheumatoid arthritis patients,” Journal of Cellular Physiology, vol. 210, no. 3, pp. 798–806, 2007. View at Publisher · View at Google Scholar · View at Scopus
  13. R. Pacifici, L. Rifas, S. Teitelbaum et al., “Spontaneous release of interleukin 1 from human blood monocytes reflects bone formation in idiopathic osteoporosis,” Proceedings of the National Academy of Sciences of the United States of America, vol. 84, no. 13, pp. 4616–4620, 1987. View at Publisher · View at Google Scholar · View at Scopus
  14. R. Pacifici, L. Rifas, R. McCracken et al., “Ovarian steroid treatment blocks a postmenopausal increase in blood monocyte interleukin 1 release,” Proceedings of the National Academy of Sciences of the United States of America, vol. 86, no. 7, pp. 2398–2402, 1989. View at Publisher · View at Google Scholar · View at Scopus