Potential Effects of Corneal Cross-Linking upon the Limbus

Table 2

Devices used for CXL and their different features [2].

UV device	Procedure	Irradiance	Spot sizes
XLink™ (Optos, Dunfermline, UK)	Standard 30 min CXL	0.5–5 mW/cm^2	6, 8, and 10 mm
CBM Vega XLink Cross-Linking System (Carleton Optical, Chesham, UK)	Standard 30-min CXL	3 mW/cm^2	4 to 11 mm
The LightLink CXL™ (LightMed, San Clemente, Calif., USA)	From 3 to 30 min length protocols	Between 0.5 and 30 mW/cm^2	4 to 11 mm
The UV-X™ 2000 Cross-Linking System (IROC Innocross, Zurich, Switzerland)	Used for in a 10 min accelerated CXL procedure	12 mW/cm^2	7.5 mm, 9.5 mm
KXL™ System (Avedro, Waltham, Mass., USA)	Used in ultrafast accelerated CXL (<3 min of UVA exposure). It gave a positive outcome only in a small number of KC patients and in combination with the LASEK procedure	Intensity of 30 mW/cm^2	Up to 11 mm