Regulation of Human Cytochrome P4501A1 (hCYP1A1): A Plausible Target for Chemoprevention?

Figure 2

Mechanisms involved in the CYP1A1 regulation. Pathways implicated in up- and downregulation of CYP1A1 are shown, as well as changes in epigenetic marks upon the induction of this gene. The “?” symbol means pathways that had not been proved in human models, specified along the text. Image was created using PathVisio program [42] and edited with Adobe Illustrator CC 2015.0.0 program.