Relationship between Antibody Levels, IgG Binding to Plasmodium falciparum-Infected Erythrocytes, and Disease Outcome in Hospitalized Urban Malaria Patients from Dakar, Sénégal

Figure 4

Relationship between labeled index of recognition and IgG responses in MM (a) and CM (b–d) groups. The correlations between labeled index of recognition (LIR) and IgG anti-iRBCm levels (OD ratio) are plotted in MM patients (a) (dark circles) and in CM group (b) with a dichotomization in fatal CM (dark squares) and surviving CM (open circles). Relationships between LIR and the levels of IgG anti-PfEMP3/5 (OD ratio) or IgG anti-PfEB200 levels (OD ratio) are, respectively, plotted in (c) and (d), only in CM surviving patients (open circles). Results from statistical analyses done by nonparametric Spearman rank test are indicated.

(a)

(b)

(c)

(d)