Research Article

Relationship between Antibody Levels, IgG Binding to Plasmodium falciparum-Infected Erythrocytes, and Disease Outcome in Hospitalized Urban Malaria Patients from Dakar, Sénégal

Table 1

Epidemiological and hematoparasitological characteristics of the study population.

ParametersCerebral malaria
()
Mean ± SE [min–max]
Mild malaria
()
Mean ± SE [min–max]
p

Gender (male/female)39/3043/29
Age (year)17.9 ± 1.8 [2–63]17.3 ± 1.2 [5–55]ns
Age groups (adults/children)39/3035/37
Parasitemia (Tr/L)30150 ± 5510 [175–452100]28348 ± 3755 [220–141000]ns
Haemoglobin (g/dL)8.4 ± 0.33 [3.3–15.1]11.5 ± 0.51 [8.3–16.1]0.031
Red blood cells count (106/µL)3.14 ± 0.13 [1.18–4.98]4.72 ± 0.18 [2.90–7.71]0.040
White blood cells count (103/µL)12.84 ± 1.15 [4.90–51.10]8.21 ± 1.01 [4.5–13.3]0.012
Platelet count (103/µL)143.4 ± 16.2 [11–533]168.2 ± 11.8 [28–355]ns
Hematocrit (%)31.1 ± 0.22 [10.5–46.1]35.9 ± 0.18 [23.9–49.1]ns

SE = standard error, Min = minimum, Max = maximum, ns = nonsignificant, and = number of patients. Data were determined by the hospital’s medical laboratory. Adults were patients ≥15 years and children were patients 15 years. = value of comparison between CM and MM groups with Mann-Whitney rank test.