Cri-Du-Chat Syndrome: Clinical Profile and Chromosomal Microarray Analysis in Six Patients
Table 2
Cognitive, psychosocial, and motor development in six patients with 5p deletion.
Behavioral aspects and skills
Patients
Total
1
2
3
4
5
6
Friendly personality
+
+
+
+
+
+
6/6
Problems in coordinating movements
−
+
+
−
−
+
3/6
Difficulties in interacting with peers
−
+
+
−
−
+
3/6
Hyperactivity/impulsiveness
−
+
+
−
+
+
5/6
Aggressiveness/nervousness
+
+
+
6/6
Self-mutilation
−
−
+
+
−
+
3/6
Repetitive movements
−
+
+
−
−
+
3/6
Attachment to objects
−
+
+
−
+
+
4/6
Hyperacusis
−
+
+
+
−
−
3/6
Learning difficulties (writing and reading)
+
+
+
+
+
+
6/6
Speech delay
−
+
+
−
−
+
3/6
Difficulty hearing/understanding
−
+
+
−
−
+
3/6
Inability to communicate
−
+
+
−
−
+
3/6
Difficulty in daily activities (dressing, combing, and feeding)
−
+
+
−
−
+
3/6
Under specific therapy
+
+
+
+
+
−
5/6
ID level
3.5
6.0
6.0
4.5
4.5
7.0
+, present; −, absent; ID, intellectual disability level; , nervousness during childhood; inability to clearly speak more than one word; unarticulated vocalizations and elementary nonsymbolic gestures.
