Evaluation of Potential Clinical Surrogate Markers of a Trauma Induced Alteration of Clotting Factor Activities

Table 3

Correlation of clotting factor activity and serum levels with demographic data. Table shows Spearman’s rank correlation coefficient rho with 95% confidence interval (CI). ISS: injury severity score; SBP: systolic blood pressure.

	Fibrinogen	Calcium	FII	FV	FVII	FVIII	FIX	FX	FXI	FXII	FXIII
ISS	−.36 (−.60 to −.05)	−.32 (−.59 to .02)	−.27 (−.55 to .10)	−.14 (−.46 to .24)	−.03 (−.33 to .27)	−.34 (−.64 to .03)	−.48 (−.75 to −.12)	−.18 (−.48 to .17)	−.48 (−.73 to −.11)	−.33 (−.61 to .03)	−.26 (−.56 to .06)
Age	.26 (−.02 to .52)	−.05 (−.29 to .20)	−.13 (−.39 to .14)	.09 (−.15 to .33)	.11 (−.16 to .37)	−.08 (−.33 to .18)	.09 (−.15 to .34)	−.13 (−.41 to .16)	−.03 (−.29 to .24)	.04 (−.22 to .30)	.04 (−.21 to .29)
SBP (preclinical)	.40 (.14 to .61)	.36 (.05 to .60)	.39 (.11 to .60)	.45 (.18 to .66)	.26 (−.01 to .48)	.22 (−.05 to .46)	.47 (.23 to .66)	.36 (.06 to .59)	.39 (.14 to .59)	.50 (.28 to .68)	.17 (−.11 to .44)
SBP (admission)	.35 (.02 to .62)	.39 (.09 to .62)	.41 (.11 to .65)	.40 (.15 to .60)	.24 (−.03 to .47)	.28 (−.01 to .50)	.43 (.12 to .68)	.27 (−.04 to .53)	.47 (.17 to .71)	.37 (.07 to .62)	.05 (−.30 to .34)
Temperature	.26 (−.05 to .52)	.39 (.05 to .64)	.21 (−.11 to .50)	.16 (−.15 to .45)	.00 (−.32 to .28)	.05 (−.26 to .35)	.15 (−.17 to .48)	.05 (−.28 to .36)	.23 (−.11 to .55)	.24 (−.05 to .52)	−.18 (−.47 to .14)
Time to admission	−.13 (−.44 to .17)	−.16 (−.45 to .12)	−.23 (−.48 to .09)	−.24 (−.49 to .07)	−.28 (−.57 to .08)	−.26 (−.54 to .00)	−.41 (−.64 to −.15)	−.26 (−.55 to .06)	−.48 (−.68 to −.22)	−.23 (−.51 to .10)	.07 (−.26 to .37)