Clinical Study

Efficacy of Scutellaria baicalensis for the Treatment of Hand, Foot, and Mouth Disease Associated with Encephalitis in Patients Infected with EV71: A Multicenter, Retrospective Analysis

Table 3

Adverse events (AEs) and severe AEs observed in both groups.

Variable, numberScutellaria baicalensis groupRibavirin group/Fisher ( value)

Skin allergy120— (0.0017)
Gastroenteritis00— (—)
Neurogenic pulmonary edema284.1867 (0.0407)
Brainstem encephalitis9175.4232 (0.0199)
Elevated CK-MB8198.4558 (0.0036)
Elevated ALT16277.1710 (0.0074)
Kidney damage00— (—)
Hematological disorder00— (—)

Skin allergy data were compared using Fisher’s exact test. There were no cases of gastroenteritis, kidney damage, or hematological disorders in either group. CK-MB: creatine kinase-MB; ALT: alanine aminotransferase.