Efficacy of Scutellaria baicalensis for the Treatment of Hand, Foot, and Mouth Disease Associated with Encephalitis in Patients Infected with EV71: A Multicenter, Retrospective Analysis
Table 4
Comparison of efficiency and invalid cases in the Scutellaria baicalensis group.
Variable
Efficiency ()
Invalid ()
/-test ( value)
Sex
Male
165 (53.9)
58 (54.7)
0.0201 (0.8874)
Female
141 (46.1)
48 (45.3)
Age (months)
6.4962 (0.0000)
Fever >39°C over 3 days
26 (8.5)
92 (86.8)
236.1409 (0.0000)
NS involvement
Poor spirit
207 (67.6)
76 (71.7)
0.6007 (0.4383)
Headache and vomiting
196 (64.1)
72 (67.9)
0.5192 (0.4712)
Limb jitters
12 (3.9)
46 (43.4)
101.4215 (0.0000)
Nystagmus
0 (0.0)
16 (15.1)
— (0.0000)
Ataxia
1 (0.3)
8 (7.5)
15.9781 (0.0001)
Acute flaccid paralysis
6 (1.96)
17 (16.0)
29.5981 (0.0000)
Convulsion
45 (14.7)
22 (20.8)
2.1153 (0.1458)
Irritation sign
152 (49.7)
61 (57.5)
1.9547 (0.1621)
FBG level (mmol/L)
7.3916 (0.0000)
PWBC count (×109/L)
10.0999 (0.0000)
CSF-WBC count (×106/L)
1.5829 (0.1142)
EEG abnormality
194 (63.4)
68 (64.2)
0.2566 (0.6125)
MRI abnormality
80 (26.1)
32 (30.2)
0.6507 (0.4199)
A fever of >39°C over 3 days referred to 39°C at least once a day and persisted for more than 3 days, with no downward trend. Nystagmus data were compared using Fisher’s exact test. NS: nervous system; FBG: fasting blood glucose; PWBC: peripheral white blood cells; CSF-WBC: cerebrospinal fluid-white blood cells; EEG: electroencephalograph; MRI: magnetic resonance imaging.