Research Article
Serum Sialic Acid Level Is Significantly Associated with Nonalcoholic Fatty Liver Disease in a Nonobese Chinese Population: A Cross-Sectional Study
Table 1
Characteristics of study participants with or without NAFLD.
| | Variables | With NAFLD
() | Without NAFLD
() | value | value |
| | Age (year) | 48.0 (10.9) | 42.7 (11.1) | 11.856 | <0.001 | | Gender (male/female, ) | 404/289 | 1906/3317 | 122.222 | <0.001 | | Body mass index (kg/m2) | 21.57 (1.45) | 20.73 (1.56) | 13.501 | <0.001 | | Waist circumference (cm) | 80.3 (6.3) | 75.1 (6.6) | 19.602 | <0.001 | | Systolic blood pressure (mmHg) | 124.9 (16.7) | 118.1 (15.8) | 10.496 | <0.001 | | Diastolic blood pressure (mmHg) | 76.3 (11.1) | 71.6 (10.4) | 11.102 | <0.001 | | Alanine aminotransferase (U/L) | 19.0 (14.0–27.0) | 14.0 (11.0–19.0) | 14.849 | <0.001 | | -Glutamyltransferase | 23.0 (15.0–39.0) | 15.0 (11.0–22.0) | 16.215 | <0.001 | | Triglyceride (mmol/L) | 1.32 (0.89–1.94) | 0.89 (0.67–1.24) | 16.255 | <0.001 | | Total cholesterol (mmol/L) | 4.77 (4.15–5.50) | 4.51 (3.98–5.08) | 7.189 | <0.001 | | HDL cholesterol (mmol/L) | 1.27 (0.34) | 1.40 (0.32) | 10.076 | <0.001 | | LDL cholesterol (mmol/L) | 2.67 (0.73) | 2.50 (0.64) | 6.479 | <0.001 | | Fasting plasma glucose (mmol/L) | 4.83 (4.53–5.23) | 4.69 (4.44–4.95) | 8.945 | <0.001 | | Serum uric acid (mol/L) | 327.6 (85.0) | 284.7 (74.4) | 13.986 | <0.001 | | Serum sialic acid (mg/dL) | 61.1 (7.3) | 58.2 (6.9) | 10.263 | <0.001 |
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Data are expressed as mean (SD) or median (IQR).
χ2 value; Z value; HDL: high-density lipoprotein; LDL: low-density lipoprotein.
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