Recombinant Brain Natriuretic Peptide for the Prevention of Contrast-Induced Nephropathy in Patients with Chronic Kidney Disease Undergoing Nonemergent Percutaneous Coronary Intervention or Coronary Angiography: A Randomized Controlled Trial
Table 1
Baseline characteristics of the patients.
Variables
Control group (−) ()
BNP group (+) ()
Sex (male), (%)
63 (61.2%)
70 (66.0%)
0.464
Age (years)
69.8 ± 6.7
67.6 ± 7.2
0.512
Body mass index (kg/m2)
25.4 ± 4.2
24.9 ± 5.0
0.419
SBP
133.4 ± 14.6
138.8 ± 13.9
0.187
Baseline serum creatinine (mol/L)
120.5 ± 14.7
117.2 ± 13.1
0.206
Estimated glomerular filtration rate (mL/min)
50.9 ± 9.3
52.3 ± 11.2
0.324
Cystatin C
1.17 ± 0.36
1.14 ± 0.22
0.275
History of diabetes mellitus, (%)
71 (68.9%)
76 (71.7%)
0.662
History of hypertension, (%)
59 (57.3%)
62 (58.5%)
0.860
Left ventricular ejection fraction, (%)
58.4 ± 10.5
61.1 ± 8.2
0.337
Isosorbide dinitrate, (%)
77 (74.8%)
75 (70.8%)
0.516
Low molecular heparin, (%)
98 (95.1%)
100 (94.3%)
0.794
Statins, (%)
102 (99%)
103 (97%)
0.622
Contrast volume (mL)
96 ± 14.5
102 ± 17.2
0.318
Contrast volume >100 mL, (%)
62 (60.2%)
65 (61.3%)
0.757
Single-vessel disease, (%)
35 (34%)
37 (34.9%)
0.888
Double-vessel disease, (%)
42 (40.8%)
46 (43.4%)
0.701
Three-vessel disease, (%)
26 (25.2%)
23 (21.7%)
0.545
Coronary angiography, (%)
36 (35%)
33 (31.1%)
0.557
PCI, (%)
67 (65%)
73 (68.9%)
0.557
Note: continuous variables are expressed as mean ± standard deviation. Categorical variables are presented as percentage. SBP: systolic blood pressure.
