A Drosophila Model for Screening Antiobesity Agents
Relationship between bmm expression and glucose contents in diets. The transgenic flies were fed with diet containing different amounts of glucose, and the salivary glands of the third-instar larvae were observed by fluorescence microscopy. GFP signal intensities measured by the MetaMorph software (e) showed that flies fed 2.5% glucose (a) showed stronger signals than flies fed 5% (b), 10% (c), and 20% (d) glucose, respectively. Real-time PCRs were used to measure the endogenous bmm mRNA expression levels of transgenic flies (f). for each treatment. The error bars represent the standard deviation. .