The Impact of Acute Matriptase Inhibition in Hepatic Inflammatory Models

Figure 3

Extracellular ROS production of HepK2 and HepK6 cell cocultures control (Co) or exposed to matriptase inhibitors (MI-432, MI-441, MI-460, or MI-461) using Amplex Red method. Results are expressed as mean values relative to controls ± SEMs. Significant differences in fluorescence intensities were found between control and MI-441-treated coculture groups (, , in HepK2 and , , in HepK6 samples).