Review Article

ABC Transporter Subfamily D: Distinct Differences in Behavior between ABCD1–3 and ABCD4 in Subcellular Localization, Function, and Human Disease

Table 1

Clinical forms of X-ALD.

PhenotypeRatio (%)Age of onset

Cerebral ALD
 Childhood cerebral ALD~383–10
 Adolescent cerebral ALD~711–21
 Adult cerebral ALD~5 21~
Adrenomyeloneuropathy (AMN)~5020–30
Addison’s only