Bioartificial Therapy of Sepsis: Changes of Norepinephrine-Dosage in Patients and Influence on Dynamic and Cell Based Liver Tests during Extracorporeal Treatments

Table 1

Patients characteristics, illness severity, premorbidity, and clinical outcome for the study cohort ().

Patient	Major diagnoses at inclusion	Source of infection	Organ failure	Premorbidity	Age; (years)	Sex; (m)	Hospital; survival
1	SS, ALI	Pneumonia, bacteremia, infection of foot, and thoracic empyema	ARF, ALI	Diabetes mellitus,; chronic heart failure	66	m	Died; (day 62)
2	SS, ALI, and endocarditis	Bacteremia, infection of sternum	ARF, ALI,; and liver failure	Diabetes mellitus	72	m	Died; (day 2)
3	Severe sepsis, thoracic empyema	Pneumonia, bacteremia	ALI	Alcohol abuse	33	m	Survived
4	SS, colitis	Peritonitis, colitis	ARF, ALI, DIC, and liver failure	Chronic heart failure	78	m	Died; (day 4)
5	SS, ALI	Pneumonia, urinary tract infection	ARF, ALI	IHD, immunosuppression	59	m	Survived
6	SS, spondylodiscitis	Pneumonia, bacteremia, spondylodiscitis, and infection of arm	Liver failure, ALI, and ARF	COPD	67	m	Died; (day 1)
7	SS, urosepsis	Pneumonia, bacteremia, and urinary tract infection	ALI, ARF, and DIC	Diabetes mellitus, IHD	76	m	Survived
8	SS, peritonitis	Bacteremia, pneumonia, and peritonitis	ALI	COPD, alcohol abuse	62	m	Died; (day 22)
9	SS, perforated aortic aneurysm	Bacteremia, pneumonia, and peritonitis	ARF, ALI	IHD, cancer	83	m	Survived
10	SS, after urgent ACB surgery	Pneumonia	ALI	Diabetes mellitus, COPD, and IHD	57	m	Survived

ACB: aortocoronary bypass.
ALI: acute lung injury.
ARF: acute renal failure.
COPD: chronic obstructive pulmonary disease.
DIC: disseminated intravascular coagulation.
IHD: ischemic heart disease.
m: male.
SS: septic shock.