Research Article

The Role of 99mTc-Annexin V Apoptosis Scintigraphy in Visualizing Early Stage Glucocorticoid-Induced Femoral Head Osteonecrosis in the Rabbit

Figure 3

Serial 99mTc-Annexin V scans in methylprednisolone treated rabbits. (a) Scans were performed before therapy and 5–8 weeks after initiation by methylprednisolone. Increasing 99mTc-Annexin V uptake is observed as early as approximately 5 weeks after the start of prednisolone treatment. (b) 99mTc-Annexin V uptake, expressed as T/N, significantly increased with time.
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