Research Article

Identification of Novel Inhibitors against Coactivator Associated Arginine Methyltransferase 1 Based on Virtual Screening and Biological Assays

Figure 2

Antiproliferative effect of DC_C11 and DC_C66 on several cancer cell lines. (a–c) Time-dependent and dose-dependent inhibitory effect of DC_C11 on HELA, K562, and MCF7 within 24 hrs, 48 hrs, and 72 hrs, respectively. (d–f) Time-dependent and dose-dependent inhibitory effect of DC_C66 on HELA, K562, and MCF7 within 24 hrs, 48 hrs, and 72 hrs, respectively. (g–i) Time-dependent and dose-dependent inhibitory effect of Sinefungin on HELA, K562, and MCF7 within 24 hrs, 48 hrs, and 72 hrs, respectively.
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