Research Article

A Systematic Framework for Drug Repositioning from Integrated Omics and Drug Phenotype Profiles Using Pathway-Drug Network

Table 3

Breast cancer disease-specific pathways for each dataset.

GSE15852GSE20438GSE2043GSE2929Integrated
pathways

# of pathways
10971721143

Enriched pathways were identified by GSEA. For integration, the pathways with ( value < 0.01) were selected as significant pathways for each expression profile and their union was defined as “disease-specific pathways.”