A Comprehensive Curation Shows the Dynamic Evolutionary Patterns of Prokaryotic CRISPRs

Figure 1

More DRs remain to be detected in the database DbCRISPR. A CRISPR annotation may miss (a) one complete DR or (b) two imperfect DRs in the flanking regions. (c) Some CRISPR spacers may harbor truncated DRs, which are partially identical to the hosting CRISPR’s DRs. And (d) many CRISPRs have DRs broken by transposon insertions. DRs and spacers are represented by gray and white boxes, respectively. The new regions added to the DbCRISPR annotations are boxed in bold.

(a)

(b)

(c)

(d)