Effect of Diabetes Mellitus on Tuberculosis Treatment Outcome and Adverse Reactions in Patients Receiving Directly Observed Treatment Strategy in India: A Prospective Study

Table 3

Sputum conversion and treatment outcome of PTB patients with and without DM.

Variables	TB with DM (); (%)	TB without DM (); (%)	OR (95% CI)	value
PTB^#	37 (74.0)	154 (57.9)	2.168 (1.102–4.265)	0.023^!
EPTB^&	13 (26.0)	112 (42.1)	1
PTB patients ( in TB with DM group and   in TB without DM group)
Sputum status at 2 months
Sputum positive	10 (27.8)	37 (24.7)	1.222 (0.537–2.779)	0.633
Sputum conversion	26 (72.2)	113 (75.3)	1
Treatment outcomes				0.428
Successful outcomes			1
Cured	26 (72.2)	93 (62.0)
Treatment completed	06 (16.7)	43 (28.7)
Poor outcomes			1.176 (0.310–4.457)
Default	02 (5.6)	02 (1.3)
Failure	02 (5.6)	03 (2.0)
Died	01 (2.8)	09 (6.0)
Shifted to MDR	00	04 (2.7)

31 and 6 patients were sputum positive and sputum negative for AFB in TB with DM group. 109 and 45 patients were sputum positive and sputum negative for AFB in TB without DM group. 1 patient died before completion of IP in TB with DM group, 3 died, and 1 was shifted to MDR before completion of IP in TB without DM group.
^&All patients with EPTB in both groups had successfully completed treatment.
OR: odds ratio; calculated from binary logistic regression analysis; was considered as significant.