Dietary Biotin Supplementation Modifies Hepatic Morphology without Changes in Liver Toxicity Markers

Table 1

Effect of eight weeks of biotin supplementation on serum liver damage indicators.

Enzyme/metabolite	Units	Control	Biotin-supplemented
Aspartate aminotransferase	[U/L]	163 ± 11.0	196 ± 8.60
Alanine aminotransferase	[U/L]	32.9 ± 3.29	30.2 ± 2.40
Gamma-glutamyltransferase	[U/L]	2.77 ± 0.38	2.48 ± 0.50
Alkaline phosphatase	[U/L]	164 ± 11.0	196 ± 8.63
Total bilirubin	[µmol/L]	0.30 ± 0.040	0.22 ± 0.029
Indirect bilirubin	[mg/dL]	0.29 ± 0.071	0.22 ± 0.020
Albumin	[mg/dL]	3.28 ± 0.26	2.57 ± 0.24
Urea		52.3 ± 1.21	50.7 ± 1.89

Values are mean ± SEM. –10. .