BioMed Research International / 2016 / Article / Tab 5

Research Article

Identification and Evolutionary Analysis of Potential Candidate Genes in a Human Eating Disorder

Table 5

Evaluation of McDonald-Kreitman 2 × 2 contingency table by Fisher’s Exact Test (FET).

NonsynonymousSynonymousTotal

VGF
Within species variation271643
Fixed species differences79146225
Total106162268

Calr
Within species variation302454
Fixed species differences53944
Total356398

Htra1
Within species variation192241
Fixed species differences45163208
Total64185249

Manf
Within species variation729
Fixed species differences53944
Total124153

All known mutations within humans; differences when comparing human gene to mouse; only those polymorphisms identified by dbSNP as either synonymous or missense (nonsynonymous) are considered in this table. values less than 0.05 are considered significant.

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