Table 1: Diagnostic performance of individual antigens.

Antigens Rv3871 Rv3874 Rv3875 Rv3876 Rv3879   + − + − + − + − + − TB 298 242 56 188 110 96 102 186 112 249 49 Control 95 24 71 5 90 12 83 14 81 16 79 Sensitivity   81.21% 63.09% 32.21% 62.42% 83.56% Specificity   74.74% 94.74% 87.37% 85.26% 83.16% Youden   0.5595 0.5783 0.1958 0.4768 0.6672 PPV   90.98% 97.41% 88.89% 93.0% 93.96% NPV   55.91% 45% 44.86% 41.97% 61.72%

PPV: positive predictive value, NPV: negative predictive value, and Youden: Youden index = sensitivity + specificity – 1.