miR-940 Suppresses Tumor Cell Invasion and Migration via Regulation of CXCR2 in Hepatocellular Carcinoma
Table 1
Correlation between miR-940 and clinicopathological characteristics in 46 HCCs.
HCC parameters
Number of patients
miR-940 (−)
miR-940 (+)
Gender
Male
38
31
7
0.515
0.473
Female
8
5
3
Age
≥50 years old
36
29
7
0.080
0.777
<50 years old
10
7
3
Etiology
HBV+
38
30
8
0.000
1.000
HBV−
8
6
2
Cirrhosis
Positive
37
31
6
1.934
0.164
Negative
9
5
4
AFP (ng/mL)
≥400
29
22
7
0.021
0.885
<400
17
14
3
Tumor size
≥5 cm
26
21
5
0.012
0.913
<5 cm
20
15
5
TNM stage
I-II
25
18
7
0.584
0.445
III-IV
21
18
3
Edmondson grade
I-II
22
13
9
7.076
0.008
III-IV
24
23
1
Tumor microsatellite or multiple tumors
Yes
20
19
1
4.217
0.040
No
26
17
9
Vascular invasion
Yes
15
15
0
4.432
0.035
No
31
21
10
Recurrence and metastasis
Yes
29
26
3
4.313
0.038
No
17
10
7
miR-940 (−) indicated that miR-940 expression was downregulated in tumor tissue as compared with its adjacent nontumor tissue; miR-940 (+) indicated no downregulation of miR-940 between tumor tissue and adjacent nontumor tissue.,
